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4f9f
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP and Trehalose== | |
| + | <StructureSection load='4f9f' size='340' side='right'caption='[[4f9f]], [[Resolution|resolution]] 2.81Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4f9f]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_hygroscopicus_subsp._limoneus Streptomyces hygroscopicus subsp. limoneus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F9F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F9F FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.807Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900006:trehalose'>PRD_900006</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f9f OCA], [https://pdbe.org/4f9f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f9f RCSB], [https://www.ebi.ac.uk/pdbsum/4f9f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f9f ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VLDE_STRHL VLDE_STRHL] Involved in the biosynthesis of the antifungal agent validamycin A (PubMed:16725283). Catalyzes the condensation between GDP-valienol and validamine 7-phosphate via a nonglycosidic C-N bond formation to yield validoxylamine A 7'-phosphate (PubMed:21766819).<ref>PMID:16725283</ref> <ref>PMID:21766819</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Streptomyces hygroscopicus subsp. limoneus]] | ||
| + | [[Category: Almabruk KH]] | ||
| + | [[Category: Asamizu S]] | ||
| + | [[Category: Cavalier MC]] | ||
| + | [[Category: Lee Y-H]] | ||
| + | [[Category: Mahmud T]] | ||
| + | [[Category: Neau D]] | ||
| + | [[Category: Yim Y-S]] | ||
Current revision
Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP and Trehalose
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