4fex
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4fex is ON HOLD Authors: Stogios, P.J., Evdokimova, E., Wawrzak, Z., Minasov, G., Egorova, O., Di Leo, R., Shakya, T., Spanogiannopoulos, P., Wright...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor tyrphostin AG1478== | |
| + | <StructureSection load='4fex' size='340' side='right'caption='[[4fex]], [[Resolution|resolution]] 2.71Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4fex]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii_AYE Acinetobacter baumannii AYE]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FEX FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.71Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0TO:N-(3-CHLOROPHENYL)-6,7-DIMETHOXYQUINAZOLIN-4-AMINE'>0TO</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fex OCA], [https://pdbe.org/4fex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fex RCSB], [https://www.ebi.ac.uk/pdbsum/4fex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fex ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/B0VD92_ACIBY B0VD92_ACIBY] | ||
| - | + | ==See Also== | |
| - | + | *[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Acinetobacter baumannii AYE]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Anderson WF]] | ||
| + | [[Category: Di Leo R]] | ||
| + | [[Category: Egorova O]] | ||
| + | [[Category: Evdokimova E]] | ||
| + | [[Category: Minasov G]] | ||
| + | [[Category: Savchenko A]] | ||
| + | [[Category: Shakya T]] | ||
| + | [[Category: Spanogiannopoulos P]] | ||
| + | [[Category: Stogios PJ]] | ||
| + | [[Category: Wawrzak Z]] | ||
| + | [[Category: Wright GD]] | ||
Current revision
Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor tyrphostin AG1478
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