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3sa4

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[[Image:3sa4.jpg|left|200px]]
 
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==Crystal structure of wild-type HIV-1 protease in complex with AF72==
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The line below this paragraph, containing "STRUCTURE_3sa4", creates the "Structure Box" on the page.
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<StructureSection load='3sa4' size='340' side='right'caption='[[3sa4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3sa4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SA4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SA4 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=F72:N-{(2S,3R)-4-[(1,3-BENZOTHIAZOL-6-YLSULFONYL)(CYCLOHEXYLMETHYL)AMINO]-3-HYDROXY-1-PHENYLBUTAN-2-YL}-3-HYDROXYBENZAMIDE'>F72</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_3sa4| PDB=3sa4 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sa4 OCA], [https://pdbe.org/3sa4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sa4 RCSB], [https://www.ebi.ac.uk/pdbsum/3sa4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sa4 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O38732_9HIV1 O38732_9HIV1]
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===Crystal structure of wild-type HIV-1 protease in complex with AF72===
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==See Also==
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*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3sa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SA4 OCA].
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[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Nalam, M N.L.]]
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[[Category: Large Structures]]
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[[Category: Schiffer, C A.]]
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[[Category: Nalam MNL]]
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[[Category: Aid]]
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[[Category: Schiffer CA]]
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[[Category: Aspartyl protease]]
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[[Category: Drug design]]
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[[Category: Drug resistance]]
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[[Category: Hiv-1 protease]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Protease inhibitor]]
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Current revision

Crystal structure of wild-type HIV-1 protease in complex with AF72

PDB ID 3sa4

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