2k2q

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[[Image:2k2q.png|left|200px]]
 
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==complex structure of the external thioesterase of the Surfactin-synthetase with a carrier domain==
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The line below this paragraph, containing "STRUCTURE_2k2q", creates the "Structure Box" on the page.
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<StructureSection load='2k2q' size='340' side='right'caption='[[2k2q]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2k2q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [https://en.wikipedia.org/wiki/Brevibacillus_parabrevis Brevibacillus parabrevis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K2Q FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k2q OCA], [https://pdbe.org/2k2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k2q RCSB], [https://www.ebi.ac.uk/pdbsum/2k2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k2q ProSAT]</span></td></tr>
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{{STRUCTURE_2k2q| PDB=2k2q | SCENE= }}
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</table>
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== Function ==
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===complex structure of the external thioesterase of the Surfactin-synthetase with a carrier domain===
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[https://www.uniprot.org/uniprot/TYCC_BREPA TYCC_BREPA] Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 18704089 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k2/2k2q_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k2q ConSurf].
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[[2k2q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [http://en.wikipedia.org/wiki/Brevibacillus_parabrevis Brevibacillus parabrevis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K2Q OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:018704089</ref><references group="xtra"/>
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[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Brevibacillus parabrevis]]
[[Category: Brevibacillus parabrevis]]
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[[Category: Bernhard, F.]]
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[[Category: Large Structures]]
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[[Category: Dotsch, V.]]
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[[Category: Bernhard F]]
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[[Category: Frueh, D P.]]
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[[Category: Dotsch V]]
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[[Category: Guntert, P.]]
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[[Category: Frueh DP]]
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[[Category: Koglin, A.]]
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[[Category: Guntert P]]
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[[Category: Lohr, F.]]
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[[Category: Koglin A]]
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[[Category: Marahiel, M A.]]
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[[Category: Lohr F]]
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[[Category: Mofid, M R.]]
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[[Category: Marahiel MA]]
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[[Category: Rogov, V R.]]
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[[Category: Mofid MR]]
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[[Category: Strieter, E R.]]
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[[Category: Rogov VV]]
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[[Category: Wagner, G.]]
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[[Category: Strieter ER]]
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[[Category: Walsh, C T.]]
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[[Category: Wagner G]]
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[[Category: A/b-hydrolase]]
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[[Category: Walsh CT]]
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[[Category: Antibiotic biosynthesis]]
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[[Category: Ligase]]
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[[Category: Ligase-hydrolase complex]]
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[[Category: Multifunctional enzyme]]
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[[Category: Non-ribosomal peptide synthetase]]
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[[Category: Nrp]]
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[[Category: Phosphopantetheine]]
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[[Category: Sporulation]]
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[[Category: Stress response]]
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[[Category: Thioesterase]]
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[[Category: Type ii thioesterase]]
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Current revision

complex structure of the external thioesterase of the Surfactin-synthetase with a carrier domain

PDB ID 2k2q

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