3vcd

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[[Image:3vcd.png|left|200px]]
 
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==Computationally Designed Self-assembling Octahedral Cage protein, O333, Crystallized in space group R32==
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The line below this paragraph, containing "STRUCTURE_3vcd", creates the "Structure Box" on the page.
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<StructureSection load='3vcd' size='340' side='right'caption='[[3vcd]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3vcd]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica Salmonella enterica]. The September 2013 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Designed Protein Cages'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2013_9 10.2210/rcsb_pdb/mom_2013_9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VCD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VCD FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3vcd| PDB=3vcd | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vcd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vcd OCA], [https://pdbe.org/3vcd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vcd RCSB], [https://www.ebi.ac.uk/pdbsum/3vcd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vcd ProSAT]</span></td></tr>
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</table>
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===Computationally Designed Self-assembling Octahedral Cage protein, O333, Crystallized in space group R32===
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== Function ==
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[https://www.uniprot.org/uniprot/PDUT_SALTY PDUT_SALTY] A minor shell protein of the bacterial microcompartment (BMC) dedicated to 1,2-propanediol (1,2-PD) degradation. The isolated BMC shell component protein ratio for J:A:B':B:K:T:U is approximately 15:10:7:6:1:1:2 (PubMed:12923081). Not required for structural integrity of BMCs nor to mitigate propionaldehyde toxicity, may selectively transport specific metabolites (PubMed:21239588). May be involved in electron transport across the BMC shell (Probable). Can be engineered to alter permeability of the BMC shell (PubMed:31674899).<ref>PMID:12923081</ref> <ref>PMID:21239588</ref> <ref>PMID:31674899</ref> <ref>PMID:20870711</ref> The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.<ref>PMID:28475631</ref>
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_22654060}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22654060 is the PubMed ID number.
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</StructureSection>
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[[Category: Designed Protein Cages]]
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{{ABSTRACT_PUBMED_22654060}}
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[[Category: Large Structures]]
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[[Category: RCSB PDB Molecule of the Month]]
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==About this Structure==
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[[3vcd]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica Salmonella enterica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VCD OCA].
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==Reference==
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<ref group="xtra">PMID:022654060</ref><references group="xtra"/>
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[[Category: Salmonella enterica]]
[[Category: Salmonella enterica]]
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[[Category: Baker, D.]]
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[[Category: Baker D]]
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[[Category: King, N P.]]
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[[Category: King NP]]
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[[Category: Sawaya, M R.]]
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[[Category: Sawaya MR]]
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[[Category: Sheffler, W.]]
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[[Category: Sheffler W]]
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[[Category: Yeates, T O.]]
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[[Category: Yeates TO]]
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[[Category: Electron transport]]
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[[Category: Self assembling octahedral cage design]]
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Current revision

Computationally Designed Self-assembling Octahedral Cage protein, O333, Crystallized in space group R32

PDB ID 3vcd

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