3u25

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[[Image:3u25.png|left|200px]]
 
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==Crystal structure of P. aeruginoas azurin containing a Tyr-His hydrogen bonded pair==
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The line below this paragraph, containing "STRUCTURE_3u25", creates the "Structure Box" on the page.
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<StructureSection load='3u25' size='340' side='right'caption='[[3u25]], [[Resolution|resolution]] 1.18&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3u25]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U25 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U25 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.18&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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{{STRUCTURE_3u25| PDB=3u25 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u25 OCA], [https://pdbe.org/3u25 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u25 RCSB], [https://www.ebi.ac.uk/pdbsum/3u25 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u25 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AZUR_PSEAE AZUR_PSEAE] Transfers electrons from cytochrome c551 to cytochrome oxidase.
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Redox reactions of tyrosine play key roles in many biological processes, including water oxidation and DNA synthesis. We first review the redox properties of tyrosine (and other phenols) in small molecules and related polypeptides, then report work on (H20)/(Y48)-modified Pseudomonas aeruginosa azurin. The crystal structure of this protein (1.18A resolution) shows that H20 is strongly hydrogen bonded to Y48 (2.7-2.8A tyrosine-O to histidine-N distance). A firm conclusion is that proper tuning of the tyrosine potential by a proton-accepting base is critical for biological redox functions.
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===Crystal structure of P. aeruginoas azurin containing a Tyr-His hydrogen bonded pair===
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Redox properties of tyrosine and related molecules.,Warren JJ, Winkler JR, Gray HB FEBS Lett. 2012 Mar 9;586(5):596-602. Epub 2011 Dec 26. PMID:22210190<ref>PMID:22210190</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3u25" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_22210190}}, adds the Publication Abstract to the page
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*[[Azurin 3D structures|Azurin 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 22210190 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_22210190}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3u25]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U25 OCA].
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==Reference==
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<ref group="xtra">PMID:022210190</ref><references group="xtra"/>
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[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Gray, H B.]]
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[[Category: Gray HB]]
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[[Category: Warren, J J.]]
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[[Category: Warren JJ]]
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[[Category: Winkler, J R.]]
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[[Category: Winkler JR]]
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[[Category: Azurin]]
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[[Category: Cupredoxin]]
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[[Category: Electron transport]]
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Current revision

Crystal structure of P. aeruginoas azurin containing a Tyr-His hydrogen bonded pair

PDB ID 3u25

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