4f1p

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'''Unreleased structure'''
 
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The entry 4f1p is ON HOLD until Paper Publication
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==Crystal Structure of mutant S554D for ArfGAP and ANK repeat domain of ACAP1==
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<StructureSection load='4f1p' size='340' side='right'caption='[[4f1p]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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Authors: Sun, F., Pang, X., Zhang, K., Ma, J., Zhou, Q.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4f1p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F1P FirstGlance]. <br>
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Description: Crystal Structure of mutant S554D for ArfGAP and ANK repeat domain of ACAP1
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f1p OCA], [https://pdbe.org/4f1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f1p RCSB], [https://www.ebi.ac.uk/pdbsum/4f1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f1p ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACAP1_HUMAN ACAP1_HUMAN] GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.<ref>PMID:11062263</ref> <ref>PMID:16256741</ref> <ref>PMID:17398097</ref> <ref>PMID:17664335</ref> <ref>PMID:22645133</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Ma J]]
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[[Category: Pang X]]
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[[Category: Sun F]]
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[[Category: Zhang K]]
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[[Category: Zhou Q]]

Current revision

Crystal Structure of mutant S554D for ArfGAP and ANK repeat domain of ACAP1

PDB ID 4f1p

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