4fhw
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4fhw is ON HOLD Authors: Lunde, B.M., Magler, I., Meinhart, A. Description: Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism...) |
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - MgGTP bound== | |
+ | <StructureSection load='4fhw' size='340' side='right'caption='[[4fhw]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[4fhw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FHW FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fhw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fhw OCA], [https://pdbe.org/4fhw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fhw RCSB], [https://www.ebi.ac.uk/pdbsum/4fhw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fhw ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/CID1_SCHPO CID1_SCHPO] Involved in cell cycle arrest where in association with crb2/rhp9 and chk1 it inhibits unscheduled mitosis. | ||
- | + | ==See Also== | |
- | + | *[[Poly(A) RNA polymerase|Poly(A) RNA polymerase]] | |
- | + | __TOC__ | |
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Schizosaccharomyces pombe 972h-]] | ||
+ | [[Category: Lunde BM]] | ||
+ | [[Category: Magler I]] | ||
+ | [[Category: Meinhart A]] |
Current revision
Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - MgGTP bound
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