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4fhx
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4fhx is ON HOLD Authors: Lunde, B.M., Magler, I., Meinhart, A. Description: Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - H336N mutant bound to MgATP== | |
| + | <StructureSection load='4fhx' size='340' side='right'caption='[[4fhx]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4fhx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FHX FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fhx OCA], [https://pdbe.org/4fhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fhx RCSB], [https://www.ebi.ac.uk/pdbsum/4fhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fhx ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CID1_SCHPO CID1_SCHPO] Involved in cell cycle arrest where in association with crb2/rhp9 and chk1 it inhibits unscheduled mitosis. | ||
| - | + | ==See Also== | |
| - | + | *[[Poly(A) RNA polymerase|Poly(A) RNA polymerase]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Schizosaccharomyces pombe 972h-]] | ||
| + | [[Category: Lunde BM]] | ||
| + | [[Category: Magler I]] | ||
| + | [[Category: Meinhart A]] | ||
Current revision
Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - H336N mutant bound to MgATP
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