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3s9u

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[[Image:3s9u.jpg|left|200px]]
 
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==Bacillus anthracis Dihydrofolate Reductase bound to propargyl-linked TMP analog, UCP120J==
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The line below this paragraph, containing "STRUCTURE_3s9u", creates the "Structure Box" on the page.
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<StructureSection load='3s9u' size='340' side='right'caption='[[3s9u]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3s9u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S9U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S9U FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5DR:6-ETHYL-5-[3-(4-METHOXYBIPHENYL-3-YL)PROP-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE'>5DR</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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{{STRUCTURE_3s9u| PDB=3s9u | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s9u OCA], [https://pdbe.org/3s9u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s9u RCSB], [https://www.ebi.ac.uk/pdbsum/3s9u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s9u ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q81R22_BACAN Q81R22_BACAN] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]
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===Bacillus anthracis Dihydrofolate Reductase bound to propargyl-linked TMP analog, UCP120J===
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==See Also==
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*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3s9u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S9U OCA].
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[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
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[[Category: Dihydrofolate reductase]]
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[[Category: Large Structures]]
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[[Category: Anderson, A C.]]
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[[Category: Anderson AC]]
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[[Category: Beierlein, J M.]]
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[[Category: Beierlein JM]]
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[[Category: Oxidoreductase]]
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Current revision

Bacillus anthracis Dihydrofolate Reductase bound to propargyl-linked TMP analog, UCP120J

PDB ID 3s9u

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