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3sa1

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[[Image:3sa1.jpg|left|200px]]
 
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==Bacuills anthracis Dihydrofolate Reductase bound propargyl-linked TMP analog, UCP1021==
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The line below this paragraph, containing "STRUCTURE_3sa1", creates the "Structure Box" on the page.
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<StructureSection load='3sa1' size='340' side='right'caption='[[3sa1]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3sa1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SA1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6DR:6-ETHYL-5-{3-[2-METHOXY-5-(PYRIDIN-4-YL)PHENYL]PROP-1-YN-1-YL}PYRIMIDINE-2,4-DIAMINE'>6DR</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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{{STRUCTURE_3sa1| PDB=3sa1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sa1 OCA], [https://pdbe.org/3sa1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sa1 RCSB], [https://www.ebi.ac.uk/pdbsum/3sa1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sa1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q81R22_BACAN Q81R22_BACAN] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]
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===Bacuills anthracis Dihydrofolate Reductase bound propargyl-linked TMP analog, UCP1021===
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==See Also==
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*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3sa1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SA1 OCA].
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[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
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[[Category: Dihydrofolate reductase]]
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[[Category: Large Structures]]
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[[Category: Anderson, A C.]]
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[[Category: Anderson AC]]
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[[Category: Beierlein, J M.]]
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[[Category: Beierlein JM]]
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[[Category: Oxidoreductase]]
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Current revision

Bacuills anthracis Dihydrofolate Reductase bound propargyl-linked TMP analog, UCP1021

PDB ID 3sa1

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