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4euw

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Current revision (15:09, 14 March 2024) (edit) (undo)
 
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[[Image:4euw.jpg|left|200px]]
 
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==Crystal structure of a HMG domain of transcription factor SOX-9 bound to DNA (SOX-9/DNA) from Homo sapiens at 2.77 A resolution==
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The line below this paragraph, containing "STRUCTURE_4euw", creates the "Structure Box" on the page.
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<StructureSection load='4euw' size='340' side='right'caption='[[4euw]], [[Resolution|resolution]] 2.77&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[4euw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EUW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EUW FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.77&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4euw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4euw OCA], [https://pdbe.org/4euw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4euw RCSB], [https://www.ebi.ac.uk/pdbsum/4euw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4euw ProSAT]</span></td></tr>
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{{STRUCTURE_4euw| PDB=4euw | SCENE= }}
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</table>
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== Disease ==
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===Crystal structure of a HMG domain of transcription factor SOX-9 bound to DNA (SOX-9/DNA) from Homo sapiens at 2.77 A resolution===
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[https://www.uniprot.org/uniprot/SOX9_HUMAN SOX9_HUMAN] Campomelic dysplasia;46,XX testicular disorder of sex development;46,XX ovotesticular disorder of sex development. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/SOX9_HUMAN SOX9_HUMAN] Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.
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==About this Structure==
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__TOC__
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[[4euw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EUW OCA].
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Biology, Partnership for Stem Cell.]]
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[[Category: Large Structures]]
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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[[Category: Activator]]
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[[Category: Dna-binding]]
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[[Category: Hmg domain]]
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[[Category: Jcsg]]
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[[Category: Joint center for structural genomic]]
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[[Category: Nucleus]]
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[[Category: Protein structure initiative]]
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[[Category: Protein-dna complex]]
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[[Category: Psi-biology]]
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[[Category: Structural genomic]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transcription-dna complex]]
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Current revision

Crystal structure of a HMG domain of transcription factor SOX-9 bound to DNA (SOX-9/DNA) from Homo sapiens at 2.77 A resolution

PDB ID 4euw

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