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1inl

From Proteopedia

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[[Image:1inl.png|left|200px]]
 
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==Crystal Structure of Spermidine Synthase from Thermotoga Maritima==
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The line below this paragraph, containing "STRUCTURE_1inl", creates the "Structure Box" on the page.
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<StructureSection load='1inl' size='340' side='right'caption='[[1inl]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1inl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1INL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1INL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1inl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1inl OCA], [https://pdbe.org/1inl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1inl RCSB], [https://www.ebi.ac.uk/pdbsum/1inl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1inl ProSAT], [https://www.topsan.org/Proteins/MCSG/1inl TOPSAN]</span></td></tr>
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{{STRUCTURE_1inl| PDB=1inl | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of Spermidine Synthase from Thermotoga Maritima===
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[https://www.uniprot.org/uniprot/SPEE_THEMA SPEE_THEMA] Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. It has lower affinity and lower activity towards 1,3-diaminopropane, cadaverine (1,5-diaminopentane), agmatine, thermine and spermidine (in vitro).<ref>PMID:17585781</ref> <ref>PMID:11731804</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 11731804 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/in/1inl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_11731804}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1inl ConSurf].
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[[1inl]] is a 4 chain structure of [[Spermidine Synthase]] with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1INL OCA].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Spermidine Synthase|Spermidine Synthase]]
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*[[Spermidine synthase 3D structures|Spermidine synthase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:011731804</ref><ref group="xtra">PMID:015340214</ref><references group="xtra"/>
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__TOC__
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[[Category: Spermidine synthase]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Ikeguchi, Y.]]
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[[Category: Ikeguchi Y]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: Korolev, S.]]
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[[Category: Korolev S]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Pegg AE]]
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[[Category: Pegg, A E.]]
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[[Category: Savchenko A]]
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[[Category: Savchenko, A.]]
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[[Category: Skarina T]]
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[[Category: Skarina, T.]]
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[[Category: Beta-barrel]]
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[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Rossman fold]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of Spermidine Synthase from Thermotoga Maritima

PDB ID 1inl

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