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3fpn

From Proteopedia

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[[Image:3fpn.png|left|200px]]
 
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==Crystal structure of UvrA-UvrB interaction domains==
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The line below this paragraph, containing "STRUCTURE_3fpn", creates the "Structure Box" on the page.
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<StructureSection load='3fpn' size='340' side='right'caption='[[3fpn]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3fpn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FPN FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fpn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fpn OCA], [https://pdbe.org/3fpn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fpn RCSB], [https://www.ebi.ac.uk/pdbsum/3fpn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fpn ProSAT]</span></td></tr>
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{{STRUCTURE_3fpn| PDB=3fpn | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/D0VX13_GEOSE D0VX13_GEOSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fp/3fpn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fpn ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Nucleotide excision repair is distinguished from other DNA repair pathways by its ability to process a wide range of structurally unrelated DNA lesions. In bacteria, damage recognition is achieved by the UvrA.UvrB ensemble. Here, we report the structure of the complex between the interaction domains of UvrA and UvrB. These domains are necessary and sufficient for full-length UvrA and UvrB to associate and thereby form the DNA damage-sensing complex of bacterial nucleotide excision repair. The crystal structure and accompanying biochemical analyses suggest a model for the complete damage-sensing complex.
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===Crystal structure of UvrA-UvrB interaction domains===
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A structural model for the damage-sensing complex in bacterial nucleotide excision repair.,Pakotiprapha D, Liu Y, Verdine GL, Jeruzalmi D J Biol Chem. 2009 May 8;284(19):12837-44. Epub 2009 Mar 13. PMID:19287003<ref>PMID:19287003</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_19287003}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 3fpn" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 19287003 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19287003}}
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==About this Structure==
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[[3fpn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FPN OCA].
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==See Also==
==See Also==
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*[[User:Wayne Decatur|User:Wayne Decatur]]
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*[[UvrABC|UvrABC]]
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*[[User:Wayne Decatur/3ewsSLASH3g0h Morph methods|User:Wayne Decatur/3ewsSLASH3g0h Morph methods]]
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== References ==
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*[[User:Wayne Decatur/3fpn Morph methods|User:Wayne Decatur/3fpn Morph methods]]
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<references/>
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*[[UvrA-UvrB interaction domains|UvrA-UvrB interaction domains]]
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:019287003</ref><references group="xtra"/>
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[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
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[[Category: Jeruzalmi, D.]]
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[[Category: Large Structures]]
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[[Category: Pakotiprapha, D.]]
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[[Category: Jeruzalmi D]]
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[[Category: Verdine, G L.]]
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[[Category: Pakotiprapha D]]
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[[Category: Dna binding protein]]
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[[Category: Verdine GL]]
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[[Category: Dna repair]]
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[[Category: Nucleotide excision repair]]
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[[Category: Uvra]]
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[[Category: Uvrb]]
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Current revision

Crystal structure of UvrA-UvrB interaction domains

PDB ID 3fpn

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