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CED-4 Apoptosome

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<StructureSection load="3lqq" size="350" color="" frame="true" spin="on" Scene='3lqq/Default/1' side="right" caption="Nematode CED-4 apoptosome complex with ATP and Mg+2 ion [[3lqq]]" >
[[Image:3lqq.jpg|left|200px]]
[[Image:3lqq.jpg|left|200px]]
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===Structure of the CED-4 Apoptosome ([[3lqq]])===
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{{STRUCTURE_3lqq| PDB=3lqq | SCENE=3lqq/Default/1 |CAPTION= 3lqq asymmetric unit, resolution 3.53&Aring;. <br> Click <scene name='3lqq/Biomolecule1/4'>here</scene> to display biological molecule.}}
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===Structure of the CED-4 Apoptosome===
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{{ABSTRACT_PUBMED_20434985}}
{{ABSTRACT_PUBMED_20434985}}
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==About this Structure==
==About this Structure==
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3LQQ is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LQQ OCA].
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[[3lqq]] is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LQQ OCA].
<scene name='3lqq/Default/1'>The crystallographic asymmetric unit of the solved structure is an asymmetric dimer</scene> of CED-4. <scene name='3lqq/Morph/2'>Morph showing how each monomer in the asymmetric dimer relate to each other</scene>. Be sure to spin it around because <scene name='3lqq/Morphside/3'>from the side it is easier to see the dramatic difference</scene>.<br> {{Button Toggle AnimationOnPause}}<!--When Proteopedia updates to a version of Jmol that supports the Compare command, I should upload a new pdb file with chain as a model and chain b as a model in a single pdb file and then replace this scene with a scripted compare that just compares model 2 (chain b) to model 1 (chain a).-->
<scene name='3lqq/Default/1'>The crystallographic asymmetric unit of the solved structure is an asymmetric dimer</scene> of CED-4. <scene name='3lqq/Morph/2'>Morph showing how each monomer in the asymmetric dimer relate to each other</scene>. Be sure to spin it around because <scene name='3lqq/Morphside/3'>from the side it is easier to see the dramatic difference</scene>.<br> {{Button Toggle AnimationOnPause}}<!--When Proteopedia updates to a version of Jmol that supports the Compare command, I should upload a new pdb file with chain as a model and chain b as a model in a single pdb file and then replace this scene with a scripted compare that just compares model 2 (chain b) to model 1 (chain a).-->
<scene name='3lqq/Biomolecule1/4'>The biological molecule is an octamer (tetramer of the asymmetric dimer)</scene> that forms a shape similar to a funnel.<br>
<scene name='3lqq/Biomolecule1/4'>The biological molecule is an octamer (tetramer of the asymmetric dimer)</scene> that forms a shape similar to a funnel.<br>
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{{Link Toggle FancyCartoonHighQualityView}}.
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==External Links==
==External Links==
* [http://www.nature.com/nchina/2010/100707/full/nchina.2010.77.html '''Structural biology: The funnel of death''' by Felix Cheung] at Nature China.
* [http://www.nature.com/nchina/2010/100707/full/nchina.2010.77.html '''Structural biology: The funnel of death''' by Felix Cheung] at Nature China.
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[[Category: Mitochondrion]]
[[Category: Mitochondrion]]
[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
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<br />
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Created with the participation of [[User:Wayne Decatur|Wayne Decatur]], [[User:Eran Hodis|Eran Hodis]].
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==See also==
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[[Cell death protein]]

Current revision

Nematode CED-4 apoptosome complex with ATP and Mg+2 ion 3lqq

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Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel

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