3iip

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m (Protected "3iip" [edit=sysop:move=sysop])
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[[Image:3iip.png|left|200px]]
 
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==Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series==
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The line below this paragraph, containing "STRUCTURE_3iip", creates the "Structure Box" on the page.
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<StructureSection load='3iip' size='340' side='right'caption='[[3iip]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3iip]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IIP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IIP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene></td></tr>
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{{STRUCTURE_3iip| PDB=3iip | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iip OCA], [https://pdbe.org/3iip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iip RCSB], [https://www.ebi.ac.uk/pdbsum/3iip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iip ProSAT]</span></td></tr>
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</table>
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===Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series===
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<!--
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<jmolCheckbox>
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The line below this paragraph, {{ABSTRACT_PUBMED_20036254}}, adds the Publication Abstract to the page
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/3iip_consurf.spt"</scriptWhenChecked>
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(as it appears on PubMed at http://www.pubmed.gov), where 20036254 is the PubMed ID number.
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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{{ABSTRACT_PUBMED_20036254}}
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iip ConSurf].
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==About this Structure==
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<div style="clear:both"></div>
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[[3iip]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IIP OCA].
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==See Also==
==See Also==
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*[[Directed evolution|Directed evolution]]
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*[[Kemp eliminase|Kemp eliminase]]
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*[[Kemp elimination catalyst|Kemp elimination catalyst]]
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:020036254</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Dym, O.]]
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[[Category: Large Structures]]
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[[Category: Khersonsky, O.]]
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[[Category: Dym O]]
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[[Category: Tawfik, D S.]]
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[[Category: Khersonsky O]]
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[[Category: Beta barrel]]
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[[Category: Tawfik DS]]
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[[Category: Lyase]]
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Current revision

Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series

PDB ID 3iip

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