2lui
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2lui is ON HOLD Authors: Erlendsson, S., Teilum, K. Description: Chemical Shift Assignments for the PICK1 PDZ domain fused to the C10 DAT ligand) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the PICK PDZ domain in complex with the DAT C-terminal== | |
| - | + | <StructureSection load='2lui' size='340' side='right'caption='[[2lui]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2lui]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LUI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lui OCA], [https://pdbe.org/2lui PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lui RCSB], [https://www.ebi.ac.uk/pdbsum/2lui PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lui ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PICK1_RAT PICK1_RAT] Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel.<ref>PMID:16138078</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Erlendsson S]] | ||
| + | [[Category: Gether U]] | ||
| + | [[Category: Heidarsson PO]] | ||
| + | [[Category: Madsen KL]] | ||
| + | [[Category: Poulsen FM]] | ||
| + | [[Category: Rathje M]] | ||
| + | [[Category: Teilum K]] | ||
Current revision
Structure of the PICK PDZ domain in complex with the DAT C-terminal
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