4enj

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[[Image:4enj.jpg|left|200px]]
 
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{{STRUCTURE_4enj| PDB=4enj | SCENE= }}
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==Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-hydroxyethylguanine==
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<StructureSection load='4enj' size='340' side='right'caption='[[4enj]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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===Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-hydroxyethylguanine===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4enj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ENJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ENJ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22658721}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.0989&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EHG:9-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-6-(2-HYDROXYETHOXY)-9H-PURIN-2-AMINE'>EHG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4enj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4enj OCA], [https://pdbe.org/4enj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4enj RCSB], [https://www.ebi.ac.uk/pdbsum/4enj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4enj ProSAT]</span></td></tr>
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[[4enj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ENJ OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/ATL1_SCHPO ATL1_SCHPO] Acts as a DNA damage recognition factor. Required for DNA repair from mutagenic O(6)-alkylguanine adducts. Binds O(6)-alkylguanine lesions providing a signal for other DNA repair pathways.
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<ref group="xtra">PMID:022658721</ref><references group="xtra"/>
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__TOC__
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[[Category: Schizosaccharomyces pombe]]
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</StructureSection>
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[[Category: Arvai, A S.]]
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[[Category: Large Structures]]
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[[Category: Tainer, J A.]]
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[[Category: Schizosaccharomyces pombe 972h-]]
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[[Category: Tubbs, J L.]]
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[[Category: Synthetic construct]]
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[[Category: Alkylation]]
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[[Category: Arvai AS]]
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[[Category: Alkyltransferase]]
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[[Category: Tainer JA]]
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[[Category: Base repair]]
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[[Category: Tubbs JL]]
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[[Category: Dna]]
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[[Category: Dna binding protein-dna complex]]
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[[Category: Dna damage]]
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[[Category: Dna repair]]
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[[Category: Guanine]]
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[[Category: Ner]]
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[[Category: Nucleotide excision repair]]
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Current revision

Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-hydroxyethylguanine

PDB ID 4enj

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