3scz
From Proteopedia
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| - | [[Image:3scz.jpg|left|200px]] | ||
| - | + | ==Combining crystallographic, thermodynamic, and molecular dynamics studies of Mycobacterium tuberculosis purine nucleoside phosphorylase== | |
| + | <StructureSection load='3scz' size='340' side='right'caption='[[3scz]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3scz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SCZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SCZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3scz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3scz OCA], [https://pdbe.org/3scz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3scz RCSB], [https://www.ebi.ac.uk/pdbsum/3scz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3scz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PUNA_MYCTU PUNA_MYCTU] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine and inosine (By similarity). | ||
| - | === | + | ==See Also== |
| - | + | *[[Purine nucleoside phosphorylase 3D structures|Purine nucleoside phosphorylase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | [[ | + | [[Category: Large Structures]] |
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | + | [[Category: Basso LA]] | |
| - | + | [[Category: Caceres RA]] | |
| - | [[Category: Basso | + | [[Category: Ducati RG]] |
| - | [[Category: Caceres | + | [[Category: Rosado LA]] |
| - | [[Category: Ducati | + | [[Category: Santos DS]] |
| - | [[Category: Rosado | + | [[Category: Timmers LFSM]] |
| - | [[Category: Santos | + | [[Category: De Azevedo Jr WF]] |
| - | [[Category: Timmers | + | |
| - | [[Category: | + | |
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Current revision
Combining crystallographic, thermodynamic, and molecular dynamics studies of Mycobacterium tuberculosis purine nucleoside phosphorylase
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