4f14
From Proteopedia
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- | [[Image:4f14.jpg|left|200px]] | ||
- | + | ==Structure of the SH3 domain of human nebulette in complex with a peptide of XIRP2== | |
- | + | <StructureSection load='4f14' size='340' side='right'caption='[[4f14]], [[Resolution|resolution]] 1.20Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4f14]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F14 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F14 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2Å</td></tr> | |
- | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
- | [[4f14]] is a 2 chain structure with sequence from [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f14 OCA], [https://pdbe.org/4f14 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f14 RCSB], [https://www.ebi.ac.uk/pdbsum/4f14 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f14 ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/NEBL_HUMAN NEBL_HUMAN] Binds to actin and plays an important role in the assembly of the Z-disk. Isoform 2 might play a role in the assembly of focal adhesion.<ref>PMID:15004028</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Sauer F]] |
- | [[Category: | + | [[Category: Vahokoski J]] |
- | [[Category: | + | [[Category: Wilmanns M]] |
- | + | ||
- | + |
Current revision
Structure of the SH3 domain of human nebulette in complex with a peptide of XIRP2
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