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1qow

From Proteopedia

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[[Image:1qow.png|left|200px]]
 
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{{STRUCTURE_1qow| PDB=1qow | SCENE= }}
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==Mersacidin from Bacillus==
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<StructureSection load='1qow' size='340' side='right'caption='[[1qow]], [[Resolution|resolution]] 1.06&Aring;' scene=''>
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===Mersacidin from Bacillus===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1qow]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._(in:_Bacteria) Bacillus sp. (in: Bacteria)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QOW FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10818347}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.06&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=DHA:2-AMINO-ACRYLIC+ACID'>DHA</scene>, <scene name='pdbligand=MOH:METHANOL'>MOH</scene>, <scene name='pdbligand=PRD_000199:Mersacidin'>PRD_000199</scene>, <scene name='pdbligand=TEE:2-AMINO-ETHENETHIOL'>TEE</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qow OCA], [https://pdbe.org/1qow PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qow RCSB], [https://www.ebi.ac.uk/pdbsum/1qow PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qow ProSAT]</span></td></tr>
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[[1qow]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sp. Bacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QOW OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/MRSA_BACSY MRSA_BACSY] Kills a number of Gram-positive bacteria. Acts at the level of cell wall biosynthesis by interfering with bacterial peptidoglycan biosynthesis. Specifically inhibits the conversion of the lipid II intermediate into polymeric nascent glycan strands by transglycosylation. May interact with the peptidoglycan precursor rather than with the enzyme.
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<ref group="xtra">PMID:010818347</ref><references group="xtra"/>
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__TOC__
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[[Category: Bacillus sp.]]
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</StructureSection>
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[[Category: Kaercher, J.]]
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[[Category: Large Structures]]
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[[Category: Schneider, T R.]]
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[[Category: Kaercher J]]
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[[Category: Sheldrick, G M.]]
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[[Category: Schneider TR]]
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[[Category: Antibiotic]]
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[[Category: Sheldrick GM]]
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[[Category: Lanthionine]]
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[[Category: Lantibiotic]]
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[[Category: Methicillin resistance]]
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[[Category: Thioester]]
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[[Category: Type b lantibiotic]]
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Current revision

Mersacidin from Bacillus

PDB ID 1qow

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