3efm

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[[Image:3efm.png|left|200px]]
 
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{{STRUCTURE_3efm| PDB=3efm | SCENE= }}
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==Structure of the alcaligin outer membrane recepteur FauA from Bordetella pertussis==
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<StructureSection load='3efm' size='340' side='right'caption='[[3efm]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3efm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bordetella_pertussis Bordetella pertussis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EFM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EFM FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.33&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3efm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3efm OCA], [https://pdbe.org/3efm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3efm RCSB], [https://www.ebi.ac.uk/pdbsum/3efm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3efm ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9X6A5_BORPT Q9X6A5_BORPT]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ef/3efm_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3efm ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Bordetella pertussis is the bacterial agent of whooping cough in humans. Under iron-limiting conditions, it produces the siderophore alcaligin. Released to the extracellular environment, alcaligin chelates iron, which is then taken up as a ferric alcaligin complex via the FauA outer membrane transporter. FauA belongs to a family of TonB-dependent outer membrane transporters that function using energy derived from the proton motive force. Using an in-house protocol for membrane-protein expression, purification and crystallization, FauA was crystallized in its apo form together with three other TonB-dependent transporters from different organisms. Here, the protocol used to study FauA is described and its three-dimensional structure determined at 2.3 A resolution is discussed.
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===Structure of the alcaligin outer membrane recepteur FauA from Bordetella pertussis===
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Use of an in-house approach to study the three-dimensional structures of various outer membrane proteins: structure of the alcaligin outer membrane transporter FauA from Bordetella pertussis.,Brillet K, Meksem A, Lauber E, Reimmann C, Cobessi D Acta Crystallogr D Biol Crystallogr. 2009 Apr;65(Pt 4):326-31. Epub 2009 Mar 19. PMID:19307713<ref>PMID:19307713</ref>
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{{ABSTRACT_PUBMED_19307713}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 3efm" style="background-color:#fffaf0;"></div>
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[[3efm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bordetella_pertussis Bordetella pertussis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EFM OCA].
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== References ==
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<references/>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:019307713</ref><references group="xtra"/>
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</StructureSection>
[[Category: Bordetella pertussis]]
[[Category: Bordetella pertussis]]
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[[Category: Armstrong, S K.]]
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[[Category: Large Structures]]
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[[Category: Brillet, K.]]
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[[Category: Armstrong SK]]
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[[Category: Cobessi, D.]]
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[[Category: Brillet K]]
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[[Category: Lauber, E.]]
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[[Category: Cobessi D]]
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[[Category: Reimmann, C.]]
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[[Category: Lauber E]]
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[[Category: Membrane]]
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[[Category: Reimmann C]]
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[[Category: Membrane protein]]
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[[Category: Membrane receptor]]
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[[Category: Membrane transporter]]
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[[Category: Receptor]]
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[[Category: Siderophore]]
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[[Category: Tonb box]]
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Current revision

Structure of the alcaligin outer membrane recepteur FauA from Bordetella pertussis

PDB ID 3efm

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