3th8

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[[Image:3th8.jpg|left|200px]]
 
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{{STRUCTURE_3th8| PDB=3th8 | SCENE= }}
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==Structure of E. coli undecaprenyl diphosphate synthase complexed with BPH-1063==
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<StructureSection load='3th8' size='340' side='right'caption='[[3th8]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3th8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TH8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.114&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TH9:(2Z)-4-({3-[3-(HEXYLOXY)PHENYL]PROPYL}AMINO)-2-HYDROXY-4-OXOBUT-2-ENOIC+ACID'>TH9</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3th8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3th8 OCA], [https://pdbe.org/3th8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3th8 RCSB], [https://www.ebi.ac.uk/pdbsum/3th8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3th8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/UPPS_ECOLI UPPS_ECOLI] Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.<ref>PMID:12756244</ref>
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===Structure of E. coli undecaprenyl diphosphate synthase complexed with BPH-1063===
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==See Also==
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*[[Undecaprenyl pyrophosphate synthase 3D structures|Undecaprenyl pyrophosphate synthase 3D structures]]
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{{ABSTRACT_PUBMED_22662288}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[3th8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TH8 OCA].
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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==Reference==
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[[Category: Large Structures]]
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<ref group="xtra">PMID:022662288</ref><references group="xtra"/>
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[[Category: Cao R]]
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[[Category: Di-trans,poly-cis-decaprenylcistransferase]]
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[[Category: Oldfield E]]
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[[Category: Escherichia coli]]
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[[Category: Zhang Y]]
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[[Category: Cao, R.]]
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[[Category: Zhu W]]
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[[Category: Oldfield, E.]]
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[[Category: Zhang, Y.]]
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[[Category: Zhu, W.]]
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[[Category: All helice]]
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[[Category: Farneyl diphosphate binding]]
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[[Category: Isopentenyl diphosphate binding]]
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[[Category: Prenyl transferase]]
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[[Category: Prenylation]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

Structure of E. coli undecaprenyl diphosphate synthase complexed with BPH-1063

PDB ID 3th8

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