3j05
From Proteopedia
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| - | [[Image:3j05.jpg|left|200px]] | ||
| - | + | ==Three-dimensional structure of Dengue virus serotype 1 complexed with HMAb 14c10 Fab== | |
| - | + | <SX load='3j05' size='340' side='right' viewer='molstar' caption='[[3j05]], [[Resolution|resolution]] 7.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3j05]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J05 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j05 OCA], [https://pdbe.org/3j05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j05 RCSB], [https://www.ebi.ac.uk/pdbsum/3j05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j05 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[3j05]] is a 3 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/Q689G3_9FLAV Q689G3_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS013754_004_099774] | |
| - | == | + | __TOC__ |
| - | < | + | </SX> |
[[Category: Dengue virus 1]] | [[Category: Dengue virus 1]] | ||
| - | [[Category: Alonso | + | [[Category: Large Structures]] |
| - | [[Category: Chan | + | [[Category: Alonso S]] |
| - | [[Category: Fisher | + | [[Category: Chan SH]] |
| - | [[Category: Hanson | + | [[Category: Fisher D]] |
| - | [[Category: Kemeny | + | [[Category: Hanson B]] |
| - | [[Category: Kukkaro | + | [[Category: Kemeny DM]] |
| - | [[Category: Leo | + | [[Category: Kukkaro P]] |
| - | [[Category: Lim | + | [[Category: Leo YS]] |
| - | [[Category: Lok | + | [[Category: Lim A]] |
| - | [[Category: MacAry | + | [[Category: Lok SM]] |
| - | [[Category: Ng | + | [[Category: MacAry PA]] |
| - | [[Category: Ng | + | [[Category: Ng G]] |
| - | [[Category: Ooi | + | [[Category: Ng ML]] |
| - | [[Category: Schul | + | [[Category: Ooi EE]] |
| - | [[Category: Shi | + | [[Category: Schul W]] |
| - | [[Category: Smith | + | [[Category: Shi PY]] |
| - | [[Category: Tan | + | [[Category: Smith KGC]] |
| - | [[Category: Teo | + | [[Category: Tan TT]] |
| - | [[Category: Teoh | + | [[Category: Teo EW]] |
| - | [[Category: Yip | + | [[Category: Teoh EP]] |
| - | + | [[Category: Yip A]] | |
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Current revision
Three-dimensional structure of Dengue virus serotype 1 complexed with HMAb 14c10 Fab
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