4fmw

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'''Unreleased structure'''
 
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The entry 4fmw is ON HOLD until Aug 12 2013
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==Crystal structure of methyltransferase domain of human RNA (guanine-9-) methyltransferase domain containing protein 2==
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<StructureSection load='4fmw' size='340' side='right'caption='[[4fmw]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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Authors: Dong, A., Zeng, H., Loppnau, P., Tempel, W., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Wu, H., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4fmw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FMW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FMW FirstGlance]. <br>
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Description: Crystal structure of methyltransferase domain of human RNA (guanine-9-) methyltransferase domain containing protein 2 (CASP Target)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fmw OCA], [https://pdbe.org/4fmw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fmw RCSB], [https://www.ebi.ac.uk/pdbsum/4fmw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fmw ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/TM10A_HUMAN TM10A_HUMAN] Primary microcephaly-mild intellectual disability-young-onset diabetes syndrome. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/TM10A_HUMAN TM10A_HUMAN] RNA methyltransferase.<ref>PMID:25053765</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra C]]
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[[Category: Dong A]]
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[[Category: Edwards AM]]
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[[Category: Loppnau P]]
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[[Category: Tempel W]]
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[[Category: Weigelt J]]
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[[Category: Wu H]]
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[[Category: Zeng H]]

Current revision

Crystal structure of methyltransferase domain of human RNA (guanine-9-) methyltransferase domain containing protein 2

PDB ID 4fmw

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