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4dpu

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[[Image:4dpu.jpg|left|200px]]
 
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{{STRUCTURE_4dpu| PDB=4dpu | SCENE= }}
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==Crystal structure of Staphylococcus epidermidis S192A mevalonate diphosphate decarboxylase complexed with inhibitor 6-FMVAPP and ATPgS==
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<StructureSection load='4dpu' size='340' side='right'caption='[[4dpu]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===Crystal structure of Staphylococcus epidermidis S192A mevalonate diphosphate decarboxylase complexed with inhibitor 6-FMVAPP and ATPgS===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4dpu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_epidermidis Staphylococcus epidermidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DPU FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22734632}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=FM0:(3R)-3-(FLUOROMETHYL)-3-HYDROXY-5-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PENTANOIC+ACID'>FM0</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dpu OCA], [https://pdbe.org/4dpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dpu RCSB], [https://www.ebi.ac.uk/pdbsum/4dpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dpu ProSAT]</span></td></tr>
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[[4dpu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_epidermidis Staphylococcus epidermidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DPU OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/Q9FD73_STAEP Q9FD73_STAEP]
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<ref group="xtra">PMID:022734632</ref><references group="xtra"/>
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__TOC__
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[[Category: Diphosphomevalonate decarboxylase]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Staphylococcus epidermidis]]
[[Category: Staphylococcus epidermidis]]
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[[Category: Barta, M L.]]
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[[Category: Barta ML]]
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[[Category: Geisbrecht, B V.]]
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[[Category: Geisbrecht BV]]
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[[Category: McWhorter, W J.]]
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[[Category: McWhorter WJ]]
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[[Category: Ghmp kinase family]]
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[[Category: Lyase-lyase inhibitor complex]]
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Current revision

Crystal structure of Staphylococcus epidermidis S192A mevalonate diphosphate decarboxylase complexed with inhibitor 6-FMVAPP and ATPgS

PDB ID 4dpu

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