4g54
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of a periplasmic domain of the EpsAB fusion protein of the Vibrio vulnificus type II secretion system== | |
| + | <StructureSection load='4g54' size='340' side='right'caption='[[4g54]], [[Resolution|resolution]] 1.55Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4g54]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_vulnificus Vibrio vulnificus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G54 FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g54 OCA], [https://pdbe.org/4g54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g54 RCSB], [https://www.ebi.ac.uk/pdbsum/4g54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g54 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Vibrio vulnificus utilizes the type II secretion system (T2SS), culminating in a megadalton outer membrane complex called the secretin, to translocate extracellular proteins from the periplasmic space across the outer membrane. In Aeromonas hydrophila, the general secretion pathway proteins ExeA and ExeB form an inner membrane complex which interacts with peptidoglycan and is required for the assembly of the secretin composed of ExeD. In V. vulnificus, these two proteins are fused into one protein, EpsAB. Here, the crystal structure of a periplasmic domain of EpsAB (amino acids 333-584) solved by SAD phasing is presented. The crystals belonged to space group C2 and diffracted to 1.55 A resolution. | ||
| - | + | Structure of a periplasmic domain of the EpsAB fusion protein of the Vibrio vulnificus type II secretion system.,Martynowski D, Grochulski P, Howard PS Acta Crystallogr D Biol Crystallogr. 2013 Feb;69(Pt 2):142-9. doi:, 10.1107/S0907444912042710. Epub 2013 Jan 16. PMID:23385451<ref>PMID:23385451</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| + | </div> | ||
| + | <div class="pdbe-citations 4g54" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[General secretion pathway protein 3D structures|General secretion pathway protein 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Vibrio vulnificus]] | ||
| + | [[Category: Grochulski P]] | ||
| + | [[Category: Howard SP]] | ||
| + | [[Category: Martynnowski D]] | ||
Current revision
Crystal structure of a periplasmic domain of the EpsAB fusion protein of the Vibrio vulnificus type II secretion system
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