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1lq0

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[[Image:1lq0.png|left|200px]]
 
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{{STRUCTURE_1lq0| PDB=1lq0 | SCENE= }}
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==CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE AT 2.2 ANGSTROM RESOLUTION==
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<StructureSection load='1lq0' size='340' side='right'caption='[[1lq0]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE AT 2.2 ANGSTROM RESOLUTION===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1lq0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LQ0 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11960986}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lq0 OCA], [https://pdbe.org/1lq0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lq0 RCSB], [https://www.ebi.ac.uk/pdbsum/1lq0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lq0 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1lq0]] is a 1 chain structure of [[Chitinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQ0 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/CHIT1_HUMAN CHIT1_HUMAN] Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.<ref>PMID:7592832</ref> <ref>PMID:7836450</ref> <ref>PMID:9748235</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lq/1lq0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lq0 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Chitinase|Chitinase]]
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*[[Chitinase 3D structures|Chitinase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:011960986</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Dijkstra, B W.]]
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[[Category: Large Structures]]
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[[Category: Fusetti, F.]]
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[[Category: Dijkstra BW]]
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[[Category: Rozeboom, H J.]]
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[[Category: Fusetti F]]
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[[Category: Chitin]]
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[[Category: Rozeboom HJ]]
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[[Category: Chitinase]]
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[[Category: Gaucher]]
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[[Category: Hydrolase]]
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Current revision

CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE AT 2.2 ANGSTROM RESOLUTION

PDB ID 1lq0

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