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2kx9

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[[Image:2kx9.png|left|200px]]
 
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{{STRUCTURE_2kx9| PDB=2kx9 | SCENE= }}
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==Solution Structure of the Enzyme I dimer Using Residual Dipolar Couplings and Small Angle X-Ray Scattering==
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<StructureSection load='2kx9' size='340' side='right'caption='[[2kx9]]' scene=''>
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===Solution Structure of the Enzyme I dimer Using Residual Dipolar Couplings and Small Angle X-Ray Scattering===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2kx9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KX9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KX9 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_20731394}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Hybrid , Solution NMR , X-ray solution scattering</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kx9 OCA], [https://pdbe.org/2kx9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kx9 RCSB], [https://www.ebi.ac.uk/pdbsum/2kx9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kx9 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[2kx9]] is a 2 chain structure of [[Phosphotransferase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KX9 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/PT1_ECOLI PT1_ECOLI] General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).<ref>PMID:7876255</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kx/2kx9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kx9 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Phosphotransferase|Phosphotransferase]]
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*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:020731394</ref><references group="xtra"/>
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__TOC__
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[[Category: Escherichia coli]]
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</StructureSection>
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[[Category: Phosphoenolpyruvate--protein phosphotransferase]]
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[[Category: Escherichia coli K-12]]
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[[Category: Clore, G.]]
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[[Category: Large Structures]]
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[[Category: Grishaev, A.]]
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[[Category: Clore G]]
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[[Category: Guirlando, R.]]
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[[Category: Grishaev A]]
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[[Category: Schwieters, C D.]]
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[[Category: Guirlando R]]
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[[Category: Suh, J.]]
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[[Category: Schwieters CD]]
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[[Category: Takayama, Y.]]
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[[Category: Suh J]]
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[[Category: Pt]]
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[[Category: Takayama Y]]
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[[Category: Sugar phosphotransferase system]]
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[[Category: Transferase]]
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Current revision

Solution Structure of the Enzyme I dimer Using Residual Dipolar Couplings and Small Angle X-Ray Scattering

PDB ID 2kx9

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