1xwj
From Proteopedia
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| - | [[Image:1xwj.png|left|200px]] | ||
| - | + | ==Vinculin head (1-258) in complex with the talin vinculin binding site 3 (1945-1969)== | |
| - | + | <StructureSection load='1xwj' size='340' side='right'caption='[[1xwj]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1xwj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XWJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XWJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xwj OCA], [https://pdbe.org/1xwj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xwj RCSB], [https://www.ebi.ac.uk/pdbsum/1xwj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xwj ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1xwj]] | + | == Function == |
| + | [https://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xw/1xwj_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xwj ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Talin|Talin]] | + | *[[Talin 3D structures|Talin 3D structures]] |
*[[Vinculin|Vinculin]] | *[[Vinculin|Vinculin]] | ||
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
| - | [[Category: Barsukov | + | [[Category: Large Structures]] |
| - | [[Category: Critchley | + | [[Category: Barsukov IL]] |
| - | [[Category: Emsley | + | [[Category: Critchley DR]] |
| - | [[Category: Gingras | + | [[Category: Emsley J]] |
| - | [[Category: Papagrigoriou | + | [[Category: Gingras AR]] |
| - | + | [[Category: Papagrigoriou E]] | |
| - | + | ||
| - | + | ||
Current revision
Vinculin head (1-258) in complex with the talin vinculin binding site 3 (1945-1969)
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