1yzn

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[[Image:1yzn.png|left|200px]]
 
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{{STRUCTURE_1yzn| PDB=1yzn | SCENE= }}
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==GppNHp-Bound Ypt1p GTPase==
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<StructureSection load='1yzn' size='340' side='right'caption='[[1yzn]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
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===GppNHp-Bound Ypt1p GTPase===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1yzn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YZN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YZN FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16034420}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yzn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yzn OCA], [https://pdbe.org/1yzn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yzn RCSB], [https://www.ebi.ac.uk/pdbsum/1yzn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yzn ProSAT]</span></td></tr>
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[[1yzn]] is a 1 chain structure of [[GTP-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YZN OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/YPT1_YEAST YPT1_YEAST] Involved in the trafficking of secretory vesicles from the endoplasmic reticulum (ER) to the Golgi. Regulates correct targeting and tethering of vesicles to target membranes by catalyzing the selective recruitment of proteins required for tethering and fusion onto membranes. Vesicular transport depends on shuttling of YPT1 between membrane and cytosol by GDI1, probably by recycling it to its membrane of origin after a vesicle fusion event. Required for sorting and transport of proteins from the ER through the Golgi compartment. Also involved in the recycling of membrane proteins.<ref>PMID:3286011</ref> [:]<ref>PMID:11879636</ref> <ref>PMID:12189143</ref> <ref>PMID:12802060</ref> <ref>PMID:15082776</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yz/1yzn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yzn ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[GTP-binding protein|GTP-binding protein]]
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*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:016034420</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Eathiraj, S.]]
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[[Category: Eathiraj S]]
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[[Category: Lambright, D G.]]
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[[Category: Lambright DG]]
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[[Category: Pan, X.]]
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[[Category: Pan X]]
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[[Category: Ritacco, C.]]
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[[Category: Ritacco C]]
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[[Category: Protein transport]]
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[[Category: Rab gtpase]]
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[[Category: Vesicular trafficking]]
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[[Category: Ypt1p gtpase]]
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Current revision

GppNHp-Bound Ypt1p GTPase

PDB ID 1yzn

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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