2l28

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[[Image:2l28.png|left|200px]]
 
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{{STRUCTURE_2l28| PDB=2l28 | SCENE= }}
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==Solution structure of lactobacillus casei dihydrofolate reductase apo-form, 25 conformers==
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<StructureSection load='2l28' size='340' side='right'caption='[[2l28]]' scene=''>
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===Solution structure of lactobacillus casei dihydrofolate reductase apo-form, 25 conformers===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2l28]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lacticaseibacillus_casei Lacticaseibacillus casei]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L28 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21410224}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l28 OCA], [https://pdbe.org/2l28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l28 RCSB], [https://www.ebi.ac.uk/pdbsum/2l28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l28 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[2l28]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_casei Lactobacillus casei]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L28 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/DYR_LACCA DYR_LACCA] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
==See Also==
==See Also==
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*[[Dihydrofolate reductase|Dihydrofolate reductase]]
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*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021410224</ref><references group="xtra"/>
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[[Category: Lacticaseibacillus casei]]
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[[Category: Dihydrofolate reductase]]
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[[Category: Large Structures]]
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[[Category: Lactobacillus casei]]
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[[Category: Birdsall B]]
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[[Category: Birdsall, B.]]
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[[Category: Feeney J]]
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[[Category: Feeney, J.]]
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[[Category: Polshakov VI]]
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[[Category: Polshakov, V I.]]
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[[Category: Antifolate]]
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[[Category: Co-operative binding]]
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[[Category: Dhfr]]
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[[Category: Oxidoreductase]]
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Current revision

Solution structure of lactobacillus casei dihydrofolate reductase apo-form, 25 conformers

PDB ID 2l28

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