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1ak2

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[[Image:1ak2.png|left|200px]]
 
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{{STRUCTURE_1ak2| PDB=1ak2 | SCENE= }}
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==ADENYLATE KINASE ISOENZYME-2==
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<StructureSection load='1ak2' size='340' side='right'caption='[[1ak2]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
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===ADENYLATE KINASE ISOENZYME-2===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ak2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AK2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AK2 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_8868479}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ak2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ak2 OCA], [https://pdbe.org/1ak2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ak2 RCSB], [https://www.ebi.ac.uk/pdbsum/1ak2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ak2 ProSAT]</span></td></tr>
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[[1ak2]] is a 1 chain structure of [[Adenylate kinase]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AK2 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KAD2_BOVIN KAD2_BOVIN] Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. This small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth. Plays a key role in hematopoiesis (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ak/1ak2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ak2 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Adenylate kinase|Adenylate kinase]]
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*[[Adenylate kinase 3D structures|Adenylate kinase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:008868479</ref><references group="xtra"/>
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[[Category: Adenylate kinase]]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Schlauderer, G J.]]
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[[Category: Large Structures]]
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[[Category: Schulz, G E.]]
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[[Category: Schlauderer GJ]]
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[[Category: Nucleoside monophosphate kinase]]
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[[Category: Schulz GE]]
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[[Category: Phosphotransferase]]
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Current revision

ADENYLATE KINASE ISOENZYME-2

PDB ID 1ak2

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