3siv
From Proteopedia
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- | [[Image:3siv.png|left|200px]] | ||
- | + | ==Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, dimeric form== | |
- | + | <StructureSection load='3siv' size='340' side='right'caption='[[3siv]], [[Resolution|resolution]] 3.30Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[3siv]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SIV FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.304Å</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3siv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3siv OCA], [https://pdbe.org/3siv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3siv RCSB], [https://www.ebi.ac.uk/pdbsum/3siv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3siv ProSAT]</span></td></tr> | |
- | == | + | </table> |
- | [[3siv]] is a 12 chain structure | + | == Function == |
+ | [https://www.uniprot.org/uniprot/NH2L1_HUMAN NH2L1_HUMAN] Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding.<ref>PMID:10545122</ref> <ref>PMID:17412961</ref> | ||
==See Also== | ==See Also== | ||
- | *[[Nucleoprotein|Nucleoprotein]] | + | *[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] |
- | + | *[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]] | |
- | == | + | == References == |
- | < | + | <references/> |
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Ghalei | + | [[Category: Large Structures]] |
- | [[Category: Liu | + | [[Category: Ghalei H]] |
- | [[Category: Luhrmann | + | [[Category: Liu S]] |
- | [[Category: Wahl | + | [[Category: Luhrmann R]] |
- | + | [[Category: Wahl MC]] | |
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Current revision
Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, dimeric form
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Categories: Homo sapiens | Large Structures | Ghalei H | Liu S | Luhrmann R | Wahl MC