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1bbc

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[[Image:1bbc.png|left|200px]]
 
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{{STRUCTURE_1bbc| PDB=1bbc | SCENE= }}
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==STRUCTURE OF RECOMBINANT HUMAN RHEUMATOID ARTHRITIC SYNOVIAL FLUID PHOSPHOLIPASE A2 AT 2.2 ANGSTROMS RESOLUTION==
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<StructureSection load='1bbc' size='340' side='right'caption='[[1bbc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===STRUCTURE OF RECOMBINANT HUMAN RHEUMATOID ARTHRITIC SYNOVIAL FLUID PHOSPHOLIPASE A2 AT 2.2 ANGSTROMS RESOLUTION===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1bbc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BBC FirstGlance]. <br>
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{{ABSTRACT_PUBMED_2062381}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbc OCA], [https://pdbe.org/1bbc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bbc RCSB], [https://www.ebi.ac.uk/pdbsum/1bbc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bbc ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1bbc]] is a 1 chain structure of [[Phospholipase A2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBC OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/PA2GA_HUMAN PA2GA_HUMAN] Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bb/1bbc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bbc ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Phospholipase A2|Phospholipase A2]]
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*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:002062381</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Bobbitt, J L.]]
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[[Category: Large Structures]]
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[[Category: Clawson, D K.]]
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[[Category: Bobbitt JL]]
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[[Category: Dow, E R.]]
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[[Category: Clawson DK]]
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[[Category: Gamboa, G.]]
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[[Category: Dow ER]]
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[[Category: Goodsonjunior, T.]]
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[[Category: Gamboa G]]
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[[Category: Hermann, R B.]]
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[[Category: Goodsonjunior T]]
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[[Category: Jones, N D.]]
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[[Category: Hermann RB]]
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[[Category: Kramer, R M.]]
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[[Category: Jones ND]]
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[[Category: Mcclure, D B.]]
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[[Category: Kramer RM]]
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[[Category: Mihelich, E D.]]
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[[Category: Mcclure DB]]
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[[Category: Putnam, J E.]]
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[[Category: Mihelich ED]]
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[[Category: Schevitz, R W.]]
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[[Category: Putnam JE]]
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[[Category: Sharp, J D.]]
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[[Category: Schevitz RW]]
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[[Category: Stark, D H.]]
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[[Category: Sharp JD]]
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[[Category: Teater, C.]]
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[[Category: Stark DH]]
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[[Category: Warrick, M W.]]
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[[Category: Teater C]]
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[[Category: Wery, J P.]]
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[[Category: Warrick MW]]
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[[Category: Carboxylic ester hydrolase]]
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[[Category: Wery J-P]]
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[[Category: Hydrolase]]
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Current revision

STRUCTURE OF RECOMBINANT HUMAN RHEUMATOID ARTHRITIC SYNOVIAL FLUID PHOSPHOLIPASE A2 AT 2.2 ANGSTROMS RESOLUTION

PDB ID 1bbc

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