5icd

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[[Image:5icd.png|left|200px]]
 
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{{STRUCTURE_5icd| PDB=5icd | SCENE= }}
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==REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE==
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<StructureSection load='5icd' size='340' side='right'caption='[[5icd]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5icd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ICD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ICD FirstGlance]. <br>
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{{ABSTRACT_PUBMED_2204109}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ICT:ISOCITRIC+ACID'>ICT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5icd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5icd OCA], [https://pdbe.org/5icd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5icd RCSB], [https://www.ebi.ac.uk/pdbsum/5icd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5icd ProSAT]</span></td></tr>
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[[5icd]] is a 1 chain structure of [[Ferguson sandbox 1]] and [[Isocitrate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ICD OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IDH_ECOLI IDH_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ic/5icd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=5icd ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Ferguson sandbox 1|Ferguson sandbox 1]]
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*[[Isocitrate dehydrogenase 3D structures|Isocitrate dehydrogenase 3D structures]]
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*[[Isocitrate dehydrogenase|Isocitrate dehydrogenase]]
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:002204109</ref><ref group="xtra">PMID:020505668</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Dean, A M.]]
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[[Category: Large Structures]]
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[[Category: Hurley, J H.]]
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[[Category: Dean AM]]
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[[Category: Koshlandjunior, D E.]]
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[[Category: Hurley JH]]
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[[Category: Sohl, J L.]]
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[[Category: Koshlandjunior DE]]
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[[Category: Stroud, R M.]]
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[[Category: Sohl JL]]
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[[Category: Stroud RM]]

Current revision

REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE

PDB ID 5icd

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