1nl3
From Proteopedia
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| - | [[Image:1nl3.png|left|200px]] | ||
| - | + | ==CRYSTAL STRUCTURE OF THE SECA PROTEIN TRANSLOCATION ATPASE FROM MYCOBACTERIUM TUBERCULOSIS in APO FORM== | |
| - | + | <StructureSection load='1nl3' size='340' side='right'caption='[[1nl3]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1nl3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NL3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NL3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nl3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nl3 OCA], [https://pdbe.org/1nl3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nl3 RCSB], [https://www.ebi.ac.uk/pdbsum/1nl3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nl3 ProSAT], [https://www.topsan.org/Proteins/TBSGC/1nl3 TOPSAN]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1nl3]] is a 2 chain structure | + | == Function == |
| + | [https://www.uniprot.org/uniprot/SECA1_MYCTU SECA1_MYCTU] Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of precursor proteins, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nl/1nl3_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nl3 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| + | *[[Preprotein translocase 3D structures|Preprotein translocase 3D structures]] | ||
*[[SecA|SecA]] | *[[SecA|SecA]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | < | + | [[Category: Large Structures]] |
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: Arockiasamy | + | [[Category: Arockiasamy A]] |
| - | [[Category: Braunstein | + | [[Category: Braunstein M]] |
| - | [[Category: Holzenburg | + | [[Category: Holzenburg A]] |
| - | [[Category: Jacobs | + | [[Category: Jacobs Jr WR]] |
| - | [[Category: Ronning | + | [[Category: Ronning DR]] |
| - | [[Category: Sacchettini | + | [[Category: Sacchettini JC]] |
| - | [[Category: Savva | + | [[Category: Savva CG]] |
| - | [[Category: Sharma | + | [[Category: Sharma V]] |
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Current revision
CRYSTAL STRUCTURE OF THE SECA PROTEIN TRANSLOCATION ATPASE FROM MYCOBACTERIUM TUBERCULOSIS in APO FORM
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