1ad2

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[[Image:1ad2.png|left|200px]]
 
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{{STRUCTURE_1ad2| PDB=1ad2 | SCENE= }}
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==RIBOSOMAL PROTEIN L1 MUTANT WITH SERINE 179 REPLACED BY CYSTEINE==
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<StructureSection load='1ad2' size='340' side='right'caption='[[1ad2]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===RIBOSOMAL PROTEIN L1 MUTANT WITH SERINE 179 REPLACED BY CYSTEINE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ad2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AD2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AD2 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_9247141}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ad2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ad2 OCA], [https://pdbe.org/1ad2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ad2 RCSB], [https://www.ebi.ac.uk/pdbsum/1ad2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ad2 ProSAT]</span></td></tr>
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[[1ad2]] is a 1 chain structure of [[Ribosomal protein L1]] with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AD2 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RL1_THETH RL1_THETH] The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.[HAMAP-Rule:MF_01318] Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA (By similarity).[HAMAP-Rule:MF_01318]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ad/1ad2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ad2 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Ribosomal protein L1|Ribosomal protein L1]]
*[[Ribosomal protein L1|Ribosomal protein L1]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:009247141</ref><ref group="xtra">PMID:009247142</ref><ref group="xtra">PMID:011742118</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Al-Karadaghi, S.]]
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[[Category: Al-Karadaghi S]]
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[[Category: Eliseikina, I.]]
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[[Category: Eliseikina I]]
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[[Category: Fomenkova, N.]]
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[[Category: Fomenkova N]]
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[[Category: Garber, M.]]
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[[Category: Garber M]]
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[[Category: Jonsson, B H.]]
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[[Category: Jonsson B-H]]
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[[Category: Liljas, A.]]
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[[Category: Liljas A]]
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[[Category: Nevskaya, N.]]
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[[Category: Nevskaya N]]
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[[Category: Nikonov, S.]]
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[[Category: Nikonov S]]
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[[Category: Ossina, N.]]
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[[Category: Ossina N]]
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[[Category: Unge, J.]]
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[[Category: Unge J]]
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[[Category: Mutant]]
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[[Category: Protein synthesis]]
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[[Category: Ribosomal protein]]
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[[Category: Rna binding]]
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Current revision

RIBOSOMAL PROTEIN L1 MUTANT WITH SERINE 179 REPLACED BY CYSTEINE

PDB ID 1ad2

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