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3kfo

From Proteopedia

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[[Image:3kfo.png|left|200px]]
 
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{{STRUCTURE_3kfo| PDB=3kfo | SCENE= }}
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==Crystal structure of the C-terminal domain from the nuclear pore complex component NUP133 from Saccharomyces cerevisiae==
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<StructureSection load='3kfo' size='340' side='right'caption='[[3kfo]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===Crystal structure of the C-terminal domain from the nuclear pore complex component NUP133 from Saccharomyces cerevisiae===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3kfo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KFO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3KFO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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==About this Structure==
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[3kfo]] is a 1 chain structure of [[Nucleoporin]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KFO OCA].
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NUP133, RAT3, YKR082W, YKR402 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3kfo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kfo OCA], [http://pdbe.org/3kfo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kfo RCSB], [http://www.ebi.ac.uk/pdbsum/3kfo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kfo ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NU133_YEAST NU133_YEAST]] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP133 is involved in nuclear poly(A)+ RNA, tRNA and pre-ribosome export, in GSP1 nuclear import, in NPC assembly and distribution, as well as in nuclear envelope organization.<ref>PMID:7813444</ref> <ref>PMID:7862658</ref> <ref>PMID:8524308</ref> <ref>PMID:9049242</ref> <ref>PMID:11071906</ref> <ref>PMID:11823431</ref> <ref>PMID:12730220</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kf/3kfo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kfo ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Nucleoporin|Nucleoporin]]
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*[[Nucleoporin 3D structures|Nucleoporin 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:021365675</ref><references group="xtra"/>
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__TOC__
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[[Category: Saccharomyces cerevisiae]]
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</StructureSection>
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[[Category: Almo, S.]]
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[[Category: Atcc 18824]]
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[[Category: Atwell, S.]]
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[[Category: Large Structures]]
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[[Category: Bain, K.]]
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[[Category: Almo, S C]]
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[[Category: Bonanno, J B.]]
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[[Category: Atwell, S]]
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[[Category: Burley, S K.]]
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[[Category: Bain, K]]
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[[Category: Dickey, M.]]
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[[Category: Bonanno, J B]]
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[[Category: Emtage, J S.]]
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[[Category: Burley, S K]]
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[[Category: Fernandez-Martinez, J.]]
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[[Category: Dickey, M]]
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[[Category: Franke, J D.]]
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[[Category: Emtage, J S]]
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[[Category: Gheyi, T.]]
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[[Category: Fernandez-Martinez, J]]
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[[Category: Miller, S.]]
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[[Category: Franke, J D]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
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[[Category: Gheyi, T]]
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[[Category: Phillips, J.]]
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[[Category: Miller, S]]
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[[Category: Pieper, U.]]
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[[Category: Structural genomic]]
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[[Category: Rout, M.]]
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[[Category: Phillips, J]]
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[[Category: Sali, A.]]
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[[Category: Pieper, U]]
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[[Category: Sampathkumar, P.]]
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[[Category: Rout, M]]
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[[Category: Sauder, J M.]]
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[[Category: Sali, A]]
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[[Category: Thompson, D A.]]
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[[Category: Sampathkumar, P]]
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[[Category: Wasserman, S.]]
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[[Category: Sauder, J M]]
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[[Category: Thompson, D A]]
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[[Category: Wasserman, S]]
[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Mrna transport]]
[[Category: Mrna transport]]
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[[Category: New york sgx research center for structural genomic]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: New york structural genomix research consortium]]
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[[Category: Nuclear pore complex]]
[[Category: Nuclear pore complex]]
[[Category: Nucleus]]
[[Category: Nucleus]]
[[Category: Nup133]]
[[Category: Nup133]]
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[[Category: Nysgxrc]]
 
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
[[Category: Protein transport]]
[[Category: Protein transport]]
[[Category: Proteolysis]]
[[Category: Proteolysis]]
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[[Category: Psi2]]
 
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[[Category: Structural genomic]]
 
[[Category: Translocation]]
[[Category: Translocation]]
[[Category: Transport]]
[[Category: Transport]]
[[Category: Yeast]]
[[Category: Yeast]]

Current revision

Crystal structure of the C-terminal domain from the nuclear pore complex component NUP133 from Saccharomyces cerevisiae

PDB ID 3kfo

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