1sj4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:31, 14 February 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1sj4.png|left|200px]]
 
-
{{STRUCTURE_1sj4| PDB=1sj4 | SCENE= }}
+
==Crystal structure of a C75U mutant Hepatitis Delta Virus ribozyme precursor, in Cu2+ solution==
-
 
+
<StructureSection load='1sj4' size='340' side='right'caption='[[1sj4]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-
===Crystal structure of a C75U mutant Hepatitis Delta Virus ribozyme precursor, in Cu2+ solution===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1sj4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_delta_virus Hepatitis delta virus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SJ4 FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_15141216}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sj4 OCA], [https://pdbe.org/1sj4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sj4 RCSB], [https://www.ebi.ac.uk/pdbsum/1sj4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sj4 ProSAT]</span></td></tr>
-
==About this Structure==
+
</table>
-
[[1sj4]] is a 2 chain structure of [[Nucleoprotein]] and [[Ribozyme]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_delta_virus Hepatitis delta virus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJ4 OCA].
+
== Function ==
 +
[https://www.uniprot.org/uniprot/SNRPA_HUMAN SNRPA_HUMAN] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5'-UGCAC-3' motif in vitro.<ref>PMID:9848648</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sj/1sj4_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sj4 ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Nucleoprotein|Nucleoprotein]]
+
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
-
*[[Ribozyme|Ribozyme]]
+
*[[Ribozyme 3D structures|Ribozyme 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:015141216</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
[[Category: Hepatitis delta virus]]
[[Category: Hepatitis delta virus]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Cate, J H.]]
+
[[Category: Large Structures]]
-
[[Category: Ding, F.]]
+
[[Category: Cate JH]]
-
[[Category: Doudna, J A.]]
+
[[Category: Ding F]]
-
[[Category: Ke, A.]]
+
[[Category: Doudna JA]]
-
[[Category: Zhou, K.]]
+
[[Category: Ke A]]
-
[[Category: Hdv]]
+
[[Category: Zhou K]]
-
[[Category: Precurosr]]
+
-
[[Category: Ribozyme]]
+
-
[[Category: Rna]]
+
-
[[Category: Translation-rna complex]]
+
-
[[Category: U1a]]
+

Current revision

Crystal structure of a C75U mutant Hepatitis Delta Virus ribozyme precursor, in Cu2+ solution

PDB ID 1sj4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1sj4"
Personal tools