1oxu

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[[Image:1oxu.png|left|200px]]
 
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{{STRUCTURE_1oxu| PDB=1oxu | SCENE= }}
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==Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus==
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<StructureSection load='1oxu' size='340' side='right'caption='[[1oxu]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1oxu]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OXU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OXU FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12823973}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oxu OCA], [https://pdbe.org/1oxu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oxu RCSB], [https://www.ebi.ac.uk/pdbsum/1oxu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oxu ProSAT]</span></td></tr>
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[[1oxu]] is a 3 chain structure of [[ABC transporter]] with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OXU OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GLCV_SACS2 GLCV_SACS2] Part of the ABC transporter complex GlcSTUV involved in glucose uptake (Probable). Responsible for energy coupling to the transport system (PubMed:12823973, PubMed:14607117). In vitro, as a free subunit, exhibits a constitutive ATPase activity (PubMed:11807278).<ref>PMID:11807278</ref> <ref>PMID:12823973</ref> <ref>PMID:14607117</ref> <ref>PMID:10400586</ref> <ref>PMID:11260467</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ox/1oxu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oxu ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[ABC transporter|ABC transporter]]
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*[[ABC transporter 3D structures|ABC transporter 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:012823973</ref><references group="xtra"/>
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__TOC__
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[[Category: Sulfolobus solfataricus]]
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</StructureSection>
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[[Category: Albers, S V.]]
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[[Category: Large Structures]]
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[[Category: Dijkstra, B W.]]
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[[Category: Saccharolobus solfataricus]]
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[[Category: Driessen, A J.]]
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[[Category: Albers SV]]
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[[Category: Thunnissen, A M.]]
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[[Category: Dijkstra BW]]
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[[Category: Verdon, G.]]
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[[Category: Driessen AJ]]
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[[Category: Abc-atpase]]
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[[Category: Thunnissen AM]]
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[[Category: Atp-binding cassette]]
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[[Category: Verdon G]]
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[[Category: Atpase]]
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[[Category: Glcv]]
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[[Category: Sulfolobus solfataricus]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus

PDB ID 1oxu

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