1l9g

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[[Image:1l9g.png|left|200px]]
 
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{{STRUCTURE_1l9g| PDB=1l9g | SCENE= }}
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==CRYSTAL STRUCTURE OF URACIL-DNA GLYCOSYLASE FROM T. MARITIMA==
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<StructureSection load='1l9g' size='340' side='right'caption='[[1l9g]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF URACIL-DNA GLYCOSYLASE FROM T. MARITIMA===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1l9g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L9G FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[1l9g]] is a 1 chain structure of [[DNA glycosylate]] with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9G OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l9g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9g OCA], [https://pdbe.org/1l9g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l9g RCSB], [https://www.ebi.ac.uk/pdbsum/1l9g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l9g ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1l9g TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/UDGA_THEMA UDGA_THEMA] Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP. Can remove uracil from double-stranded DNA containing either a U/G or U/A base pair as well as from single-stranded DNA.<ref>PMID:10339434</ref> <ref>PMID:11267830</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l9/1l9g_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l9g ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[DNA glycosylate|DNA glycosylate]]
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*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Almo, S C.]]
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[[Category: Almo SC]]
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[[Category: Bresnik, A.]]
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[[Category: Bresnik A]]
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[[Category: Burley, S K.]]
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[[Category: Burley SK]]
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[[Category: Chance, M R.]]
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[[Category: Chance MR]]
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[[Category: Dodatko, T.]]
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[[Category: Dodatko T]]
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[[Category: Franklin, W A.]]
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[[Category: Franklin WA]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
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[[Category: Rajashankar KR]]
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[[Category: Rajashankar, K R.]]
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[[Category: Sandigursky M]]
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[[Category: Sandigursky, M.]]
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[[Category: Thirumuruhan RA]]
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[[Category: Thirumuruhan, R A.]]
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[[Category: Base excision repair]]
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[[Category: Dna glycosylase]]
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[[Category: Hydrolase]]
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[[Category: New york sgx research center for structural genomic]]
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[[Category: Nysgxrc]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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[[Category: Thermophile]]
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[[Category: Uracil]]
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Current revision

CRYSTAL STRUCTURE OF URACIL-DNA GLYCOSYLASE FROM T. MARITIMA

PDB ID 1l9g

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