3gvi

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[[Image:3gvi.png|left|200px]]
 
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{{STRUCTURE_3gvi| PDB=3gvi | SCENE= }}
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==Crystal structure of Lactate/malate dehydrogenase from Brucella melitensis in complex with ADP==
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<StructureSection load='3gvi' size='340' side='right'caption='[[3gvi]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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===Crystal structure of Lactate/malate dehydrogenase from Brucella melitensis in complex with ADP===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3gvi]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Brucella_abortus_2308 Brucella abortus 2308]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GVI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GVI FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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[[3gvi]] is a 6 chain structure of [[Johnson sandbox 1]] and [[Malate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Brucella_melitensis_biovar_abortus_2308 Brucella melitensis biovar abortus 2308]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GVI OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gvi OCA], [https://pdbe.org/3gvi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gvi RCSB], [https://www.ebi.ac.uk/pdbsum/3gvi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gvi ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MDH_BRUA2 MDH_BRUA2] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_00487]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/3gvi_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gvi ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Johnson sandbox 1|Johnson sandbox 1]]
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*[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]]
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*[[Malate dehydrogenase|Malate dehydrogenase]]
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__TOC__
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[[Category: Brucella melitensis biovar abortus 2308]]
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</StructureSection>
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[[Category: Malate dehydrogenase]]
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[[Category: Brucella abortus 2308]]
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[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
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[[Category: Large Structures]]
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[[Category: Brucella melitensis]]
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[[Category: Lactate/malate dehydrogenase]]
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[[Category: Nad]]
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[[Category: Oxidoreductase]]
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[[Category: Seattle structural genomics center for infectious disease]]
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[[Category: Ssgcid]]
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[[Category: Structural genomic]]
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[[Category: Tricarboxylic acid cycle]]
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Current revision

Crystal structure of Lactate/malate dehydrogenase from Brucella melitensis in complex with ADP

PDB ID 3gvi

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