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1d5a

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[[Image:1d5a.png|left|200px]]
 
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{{STRUCTURE_1d5a| PDB=1d5a | SCENE= }}
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==CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK. DEPOSITION OF SECOND NATIVE STRUCTURE AT 2.4 ANGSTROM==
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<StructureSection load='1d5a' size='340' side='right'caption='[[1d5a]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK. DEPOSITION OF SECOND NATIVE STRUCTURE AT 2.4 ANGSTROM===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1d5a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfurococcus_sp._Tok Desulfurococcus sp. Tok]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D5A FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10545321}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d5a OCA], [https://pdbe.org/1d5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d5a RCSB], [https://www.ebi.ac.uk/pdbsum/1d5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d5a ProSAT]</span></td></tr>
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[[1d5a]] is a 1 chain structure of [[DNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Desulfurococcus_sp._tok Desulfurococcus sp. tok]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D5A OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPOL_DESST DPOL_DESST] Thermostable DNA polymerase. In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity.<ref>PMID:8663453</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d5/1d5a_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d5a ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[DNA polymerase|DNA polymerase]]
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:010545321</ref><references group="xtra"/>
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__TOC__
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[[Category: DNA-directed DNA polymerase]]
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</StructureSection>
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[[Category: Desulfurococcus sp. tok]]
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[[Category: Desulfurococcus sp. Tok]]
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[[Category: Jeruzalmi, D.]]
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[[Category: Large Structures]]
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[[Category: Kuriyan, J.]]
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[[Category: Jeruzalmi D]]
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[[Category: Lasken, R.]]
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[[Category: Kuriyan J]]
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[[Category: Leighton, L.]]
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[[Category: Lasken R]]
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[[Category: Zhao, Y.]]
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[[Category: Leighton L]]
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[[Category: Dna polymerase]]
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[[Category: Zhao Y]]
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[[Category: Exonuclease]]
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[[Category: Rbd domain]]
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[[Category: Thermostable]]
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[[Category: Transferase]]
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Current revision

CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK. DEPOSITION OF SECOND NATIVE STRUCTURE AT 2.4 ANGSTROM

PDB ID 1d5a

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