This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ogq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:34, 21 February 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3ogq.png|left|200px]]
 
-
{{STRUCTURE_3ogq| PDB=3ogq | SCENE= }}
+
==Crystal Structure of 6s-98S FIV Protease with Lopinavir bound==
-
 
+
<StructureSection load='3ogq' size='340' side='right'caption='[[3ogq]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
===Crystal Structure of 6s-98S FIV Protease with Lopinavir bound===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3ogq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Feline_immunodeficiency_virus Feline immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OGQ FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_21636894}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AB1:N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE'>AB1</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ogq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ogq OCA], [https://pdbe.org/3ogq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ogq RCSB], [https://www.ebi.ac.uk/pdbsum/3ogq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ogq ProSAT]</span></td></tr>
-
[[3ogq]] is a 2 chain structure of [[Virus protease]] with sequence from [http://en.wikipedia.org/wiki/Feline_immunodeficiency_virus Feline immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OGQ OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/POL_FIVPE POL_FIVPE] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
==See Also==
==See Also==
-
*[[Virus protease|Virus protease]]
+
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:021636894</ref><references group="xtra"/>
+
[[Category: Feline immunodeficiency virus]]
[[Category: Feline immunodeficiency virus]]
-
[[Category: Elder, J H.]]
+
[[Category: Large Structures]]
-
[[Category: Lin, Y C.]]
+
[[Category: Elder JH]]
-
[[Category: Perryman, A L.]]
+
[[Category: Lin Y-C]]
-
[[Category: Stout, C D.]]
+
[[Category: Perryman AL]]
-
[[Category: Aspartyl protease]]
+
[[Category: Stout CD]]
-
[[Category: Hiv-like fiv chimera]]
+
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+

Current revision

Crystal Structure of 6s-98S FIV Protease with Lopinavir bound

PDB ID 3ogq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3ogq"
Personal tools