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3u2v
From Proteopedia
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| - | [[Image:3u2v.png|left|200px]] | ||
| - | + | ==Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and maltohexaose== | |
| - | + | <StructureSection load='3u2v' size='340' side='right'caption='[[3u2v]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3u2v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U2V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U2V FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PRD_900035:alpha-maltohexaose'>PRD_900035</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u2v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u2v OCA], [https://pdbe.org/3u2v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u2v RCSB], [https://www.ebi.ac.uk/pdbsum/3u2v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u2v ProSAT]</span></td></tr> |
| - | [[3u2v]] is a 2 chain structure | + | </table> |
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/GLYG_HUMAN GLYG_HUMAN] Glycogen storage disease due to glycogenin deficiency. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GLYG_HUMAN GLYG_HUMAN] Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. | ||
==See Also== | ==See Also== | ||
*[[Glycogenin|Glycogenin]] | *[[Glycogenin|Glycogenin]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Chaikuad A]] |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Froese | + | [[Category: Froese DS]] |
| - | [[Category: Krysztofinska | + | [[Category: Krysztofinska E]] |
| - | [[Category: Oppermann | + | [[Category: Oppermann U]] |
| - | + | [[Category: Weigelt J]] | |
| - | [[Category: Weigelt | + | [[Category: Yue WW]] |
| - | [[Category: Yue | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
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Current revision
Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and maltohexaose
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