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1sz8

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[[Image:1sz8.png|left|200px]]
 
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{{STRUCTURE_1sz8| PDB=1sz8 | SCENE= }}
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==Crystal Structure of an Acidic Phospholipase A2 from Naja Naja Sagittifera at 1.5 A resolution==
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<StructureSection load='1sz8' size='340' side='right'caption='[[1sz8]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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===Crystal Structure of an Acidic Phospholipase A2 from Naja Naja Sagittifera at 1.5 A resolution===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1sz8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1lff 1lff]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SZ8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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[[1sz8]] is a 1 chain structure of [[Phospholipase A2]] with sequence from [http://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1lff 1lff]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZ8 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sz8 OCA], [https://pdbe.org/1sz8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sz8 RCSB], [https://www.ebi.ac.uk/pdbsum/1sz8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sz8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PA2A3_NAJSG PA2A3_NAJSG] PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sz/1sz8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sz8 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Phospholipase A2|Phospholipase A2]]
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*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Naja sagittifera]]
[[Category: Naja sagittifera]]
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[[Category: Jabeen, T.]]
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[[Category: Jabeen T]]
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[[Category: Kaur, P.]]
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[[Category: Kaur P]]
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[[Category: Sharma, S.]]
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[[Category: Sharma S]]
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[[Category: Singh, R K.]]
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[[Category: Singh RK]]
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[[Category: Singh, T P.]]
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[[Category: Singh TP]]
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[[Category: Enzyme activity]]
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[[Category: Hydrolase]]
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[[Category: Molecular conformation]]
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[[Category: Phospholipase a2]]
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Current revision

Crystal Structure of an Acidic Phospholipase A2 from Naja Naja Sagittifera at 1.5 A resolution

PDB ID 1sz8

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