1e8l
From Proteopedia
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| - | [[Image:1e8l.png|left|200px]] | ||
| - | + | ==NMR solution structure of hen lysozyme== | |
| - | + | <StructureSection load='1e8l' size='340' side='right'caption='[[1e8l]]' scene=''> | |
| - | === | + | == Structural highlights == |
| - | + | <table><tr><td colspan='2'>[[1e8l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1hwa 1hwa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E8L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E8L FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e8l OCA], [https://pdbe.org/1e8l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e8l RCSB], [https://www.ebi.ac.uk/pdbsum/1e8l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e8l ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1e8l]] is a 1 chain structure | + | == Function == |
| + | [https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e8/1e8l_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e8l ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Lysozyme 3D structures|Lysozyme 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Boyd | + | [[Category: Boyd J]] |
| - | [[Category: Buck | + | [[Category: Buck M]] |
| - | [[Category: Dobson | + | [[Category: Dobson CM]] |
| - | [[Category: Grimshaw | + | [[Category: Grimshaw SB]] |
| - | [[Category: Redfield | + | [[Category: Redfield C]] |
| - | [[Category: Schwalbe | + | [[Category: Schwalbe H]] |
| - | [[Category: Smith | + | [[Category: Smith LJ]] |
| - | [[Category: Spencer | + | [[Category: Spencer A]] |
| - | + | ||
Current revision
NMR solution structure of hen lysozyme
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Categories: Gallus gallus | Large Structures | Boyd J | Buck M | Dobson CM | Grimshaw SB | Redfield C | Schwalbe H | Smith LJ | Spencer A
