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1fcv

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[[Image:1fcv.png|left|200px]]
 
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{{STRUCTURE_1fcv| PDB=1fcv | SCENE= }}
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==CRYSTAL STRUCTURE OF BEE VENOM HYALURONIDASE IN COMPLEX WITH HYALURONIC ACID TETRAMER==
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<StructureSection load='1fcv' size='340' side='right'caption='[[1fcv]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF BEE VENOM HYALURONIDASE IN COMPLEX WITH HYALURONIC ACID TETRAMER===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1fcv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Apis_mellifera Apis mellifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FCV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FCV FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11080624}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GCU:D-GLUCURONIC+ACID'>GCU</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fcv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fcv OCA], [https://pdbe.org/1fcv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fcv RCSB], [https://www.ebi.ac.uk/pdbsum/1fcv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fcv ProSAT]</span></td></tr>
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[[1fcv]] is a 1 chain structure of [[Hyaluronidase]] with sequence from [http://en.wikipedia.org/wiki/Apis_mellifera Apis mellifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FCV OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HUGA_APIME HUGA_APIME] Hydrolyzes high molecular weight hyaluronic acid to produce small oligosaccharides (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fc/1fcv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fcv ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Hyaluronidase|Hyaluronidase]]
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*[[Hyaluronidase 3D structures|Hyaluronidase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:011080624</ref><references group="xtra"/>
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[[Category: Apis mellifera]]
[[Category: Apis mellifera]]
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[[Category: Hyaluronoglucosaminidase]]
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[[Category: Large Structures]]
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[[Category: Markovic-Housley, Z.]]
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[[Category: Markovic-Housley Z]]
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[[Category: Miglierini, G.]]
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[[Category: Miglierini G]]
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[[Category: Mueller, U.]]
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[[Category: Mueller U]]
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[[Category: Rizkallah, J P.]]
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[[Category: Rizkallah PJ]]
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[[Category: Schirmer, T.]]
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[[Category: Schirmer T]]
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[[Category: Soldatova, L.]]
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[[Category: Soldatova L]]
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[[Category: 7 stranded tim barrel]]
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[[Category: Allergen]]
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[[Category: Glycosidase family 56]]
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[[Category: Hyaluronic acid]]
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[[Category: Hydrolase]]
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Current revision

CRYSTAL STRUCTURE OF BEE VENOM HYALURONIDASE IN COMPLEX WITH HYALURONIC ACID TETRAMER

PDB ID 1fcv

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