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1wkb

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[[Image:1wkb.png|left|200px]]
 
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{{STRUCTURE_1wkb| PDB=1wkb | SCENE= }}
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==Crystal Structure of Leucyl-tRNA Synthetase from the Archaeon Pyrococcus horikoshii Reveals a Novel Editing Domain Orientation==
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<StructureSection load='1wkb' size='340' side='right'caption='[[1wkb]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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===Crystal Structure of Leucyl-tRNA Synthetase from the Archaeon Pyrococcus horikoshii Reveals a Novel Editing Domain Orientation===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1wkb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WKB FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15663927}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkb OCA], [https://pdbe.org/1wkb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wkb RCSB], [https://www.ebi.ac.uk/pdbsum/1wkb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wkb ProSAT], [https://www.topsan.org/Proteins/RSGI/1wkb TOPSAN]</span></td></tr>
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[[1wkb]] is a 1 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKB OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYL_PYRHO SYL_PYRHO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/1wkb_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wkb ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:015663927</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Leucine--tRNA ligase]]
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[[Category: Pyrococcus horikoshii]]
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[[Category: Fukunaga, R.]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Yokoyama, S.]]
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[[Category: Amino acid]]
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[[Category: Aminoacyl-trna]]
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[[Category: Aminoacylation]]
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[[Category: Editing]]
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[[Category: Leucine]]
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[[Category: Leucyl-trna synthetase]]
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[[Category: Ligase]]
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[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Fukunaga R]]
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[[Category: Rsgi]]
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[[Category: Yokoyama S]]
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[[Category: Structural genomic]]
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[[Category: Trnaleu]]
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Current revision

Crystal Structure of Leucyl-tRNA Synthetase from the Archaeon Pyrococcus horikoshii Reveals a Novel Editing Domain Orientation

PDB ID 1wkb

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